Title: La Mesilla Car Rental, NM - Search & Compare - Expedia.ca​ [La Mesilla Travel Guide](https://expedia.ca/La-Mesilla.dx553248635975872198)[Hotels in La Mesilla](https://expedia.ca/La-Mesilla-Hotels.d553248635975872198.Travel-Guide-Hotels)[Flights to La Mesilla](https://expedia.ca/Cheap-Flights-To-La-Mesilla.d553248635975872198.Travel-Guide-Flights)[La Mesilla Vacation Packages](https://expedia.ca/La-Mesilla.d553248635975872198.Destination-Travel-Guides) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # La Mesilla Car Rental ## Search and Compare from Car Companies in La Mesilla ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXCA-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself Members save 10% or more on over 1 million car rentals - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers to unlock big savings ## Top Car Deals in La Mesilla \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people La Mesilla, New Mexico, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Mesilla,%20New%20Mexico,%20United%20States%20of%20America&dpln=553248635975872198&date1=16/03/2026&date2=18/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people La Mesilla, New Mexico, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Mesilla,%20New%20Mexico,%20United%20States%20of%20America&dpln=553248635975872198&date1=16/03/2026&date2=18/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people La Mesilla, New Mexico, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Mesilla,%20New%20Mexico,%20United%20States%20of%20America&dpln=553248635975872198&date1=16/03/2026&date2=18/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people La Mesilla, New Mexico, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Mesilla,%20New%20Mexico,%20United%20States%20of%20America&dpln=553248635975872198&date1=16/03/2026&date2=18/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in La Mesilla [View all cars](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Mesilla,%20New%20Mexico,%20United%20States%20of%20America&dpln=553248635975872198&date1=16/03/2026&date2=18/03/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=CTG_SPRING_PROMO_553248635975872198) ## Frequently asked questions ### How much is a rental car per day in La Mesilla? ### Can I rent a car from Santa Fe Municipal Airport (SAF)? ### What happens if I need to cancel my La Mesilla car reservation? ### Where can I go on a road trip from La Mesilla? > - Make tracks to Albuquerque for an excellent sightseeing adventure. Roughly 113 kilometres from La Mesilla, it's home to loads of great sights such as ABQ BioPark Zoo. > - Roughly 97 kilometres away, Rio Rancho is also a hit with travellers. Make sure you take in Santa Ana Star Centre while you're in town. It's one of the reasons people love visiting this vibrant city. > - Garden of the Gods is approximately 338 kilometres from La Mesilla and is one of the region's most scenic nature spots. Pack a picnic lunch and enjoy the fresh air. ### How do I find the best car rental deals in La Mesilla with Expedia? ### How old do you have to be to rent a car in La Mesilla? ### What do you need to rent a car in La Mesilla? ### What is the cheapest car rental in La Mesilla? ### Can I rent a car for a month or longer in La Mesilla? ### Where can I find a La Mesilla car rental if I am younger than 25? ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.ca/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.ca/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.ca/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.ca/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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